WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122109
CAS#: 17437-21-7
Description: 15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
MedKoo Cat#: 122109
Name: 15-Aminopentadecanoic Acid
CAS#: 17437-21-7
Chemical Formula: C15H31NO2
Exact Mass: 257.2355
Molecular Weight: 257.42
Elemental Analysis: C, 69.99; H, 12.14; N, 5.44; O, 12.43
Synonym: 15-Aminopentadecanoic Acid
IUPAC/Chemical Name: 15-aminopentadecanoic acid
InChi Key: LDOUJNADNJHDOO-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H31NO2/c16-14-12-10-8-6-4-2-1-3-5-7-9-11-13-15(17)18/h1-14,16H2,(H,17,18)
SMILES Code: OC(CCCCCCCCCCCCCCN)=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 257.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Heubner A, Belovsky O, Müller W, Grill HJ, Manz B, Juchem M, Pollow K. Application of liquid-liquid partition chromatography in the simultaneous purification of sex-hormone-binding globulin and corticosteroid-binding globulin. J Chromatogr. 1987 Jun 26;397:419-34. doi: 10.1016/s0021-9673(01)85027-5. PMID: 2821037.
