N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122096


Description: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester is a novel cysteine binder coupled to a terminal NHS ester bound by a PEG linker. The divinyltriazine works by stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Chemical Structure

N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester

Theoretical Analysis

MedKoo Cat#: 122096
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester
Chemical Formula: C25H36N6O9
Exact Mass: 564.25
Molecular Weight: 564.600
Elemental Analysis: C, 53.18; H, 6.43; N, 14.89; O, 25.50

Price and Availability

Size Price Availability Quantity
2mg USD 800 2 Weeks
5mg USD 1300 2 Weeks
10mg USD 2150 2 Weeks
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Synonym: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester

IUPAC/Chemical Name: 2,5-dioxopyrrolidin-1-yl 2-(4,6-divinyl-1,3,5-triazin-2-yl)-4-oxo-8,11,14,17-tetraoxa-2,5-diazaicosan-20-oate


InChi Code: InChI=1S/C25H36N6O9/c1-4-19-27-20(5-2)29-25(28-19)30(3)18-21(32)26-9-11-37-13-15-39-17-16-38-14-12-36-10-8-24(35)40-31-22(33)6-7-23(31)34/h4-5H,1-2,6-18H2,3H3,(H,26,32)


Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 564.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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