WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122096
Description: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester is a novel cysteine binder coupled to a terminal NHS ester bound by a PEG linker. The divinyltriazine works by stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
MedKoo Cat#: 122096
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester
Chemical Formula: C25H36N6O9
Exact Mass: 564.2544
Molecular Weight: 564.6
Elemental Analysis: C, 53.18; H, 6.43; N, 14.89; O, 25.50
Synonym: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-NHS ester
IUPAC/Chemical Name: 2,5-dioxopyrrolidin-1-yl 2-(4,6-divinyl-1,3,5-triazin-2-yl)-4-oxo-8,11,14,17-tetraoxa-2,5-diazaicosan-20-oate
InChi Key: JSLVQRHBVRQLGO-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H36N6O9/c1-4-19-27-20(5-2)29-25(28-19)30(3)18-21(32)26-9-11-37-13-15-39-17-16-38-14-12-36-10-8-24(35)40-31-22(33)6-7-23(31)34/h4-5H,1-2,6-18H2,3H3,(H,26,32)
SMILES Code: C=CC1=NC(N(C)CC(NCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O)=O)=NC(C=C)=N1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 564.6 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|