WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122095
CAS#: N/A
Description: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-acid is a novel cysteine binder coupled to a terminal carboxylic acid bound by a PEG linker. The divinyltriazine works by stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
MedKoo Cat#: 122095
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-acid
CAS#: N/A
Chemical Formula: C21H33N5O7
Exact Mass: 467.238
Molecular Weight: 467.52
Elemental Analysis: C, 53.95; H, 7.11; N, 14.98; O, 23.95
Synonym: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-acid
IUPAC/Chemical Name: 2-(4,6-divinyl-1,3,5-triazin-2-yl)-4-oxo-8,11,14,17-tetraoxa-2,5-diazaicosan-20-oic acid
InChi Key: ZAHBVWMMOXHQPS-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H33N5O7/c1-4-17-23-18(5-2)25-21(24-17)26(3)16-19(27)22-7-9-31-11-13-33-15-14-32-12-10-30-8-6-20(28)29/h4-5H,1-2,6-16H2,3H3,(H,22,27)(H,28,29)
SMILES Code: C=CC1=NC(N(C)CC(NCCOCCOCCOCCOCCC(O)=O)=O)=NC(C=C)=N1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 467.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
