WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 122095


Description: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-acid is a novel cysteine binder coupled to a terminal carboxylic acid bound by a PEG linker. The divinyltriazine works by stapling of two cysteine residues to form macrocyclic peptides from their unprotected linear counterparts. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 122095
Name: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-acid
Chemical Formula: C21H33N5O7
Exact Mass: 467.238
Molecular Weight: 467.52
Elemental Analysis: C, 53.95; H, 7.11; N, 14.98; O, 23.95

Price and Availability

Size Price Availability Quantity
5.0mg USD 900.0 2 Weeks
10.0mg USD 1450.0 2 Weeks
25.0mg USD 2450.0 2 Weeks
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Synonym: N-(4,6-divinyl-1,3,5-triazin-2-yl)-PEG4-acid

IUPAC/Chemical Name: 2-(4,6-divinyl-1,3,5-triazin-2-yl)-4-oxo-8,11,14,17-tetraoxa-2,5-diazaicosan-20-oic acid


InChi Code: InChI=1S/C21H33N5O7/c1-4-17-23-18(5-2)25-21(24-17)26(3)16-19(27)22-7-9-31-11-13-33-15-14-32-12-10-30-8-6-20(28)29/h4-5H,1-2,6-16H2,3H3,(H,22,27)(H,28,29)


Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 467.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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