WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 122003
CAS#: N/A
Description: a heterotrifunctional linker containing two BCN moieties for click chemistry and a carboxylic acid group for amide coupling with amine. The BCN demonstrates high specific reactivity toward azide group through strain-promoted click reaction in the absence of a catalyst with least hydrophobicity among all cyclooctynes.
MedKoo Cat#: 122003
Name: ACID-PEG1-BIS-PEG3-BCN (exo)
CAS#: N/A
Chemical Formula: C51H81N5O18
Exact Mass: 1051.557
Molecular Weight: 1052.22
Elemental Analysis: C, 58.22; H, 7.76; N, 6.66; O, 27.37
Synonym:
IUPAC/Chemical Name: 1-((1R,8S,9r)-bicyclo[6.1.0]non-4-yn-9-yl)-22-(1-((1R,8S,9r)-bicyclo[6.1.0]non-4-yn-9-yl)-3,17-dioxo-2,7,10,13,20-pentaoxa-4,16-diazahenicosan-21-yl)-3,17,24-trioxo-2,7,10,13,20,26-hexaoxa-4,16,23-triazaoctacosan-28-oic acid
InChi Key: GUNWFXDIBGHKDR-DWVQWBRISA-N
InChi Code: InChI=1S/C51H81N5O18/c57-46(52-15-21-64-25-29-68-31-27-66-23-17-54-50(62)73-35-44-40-9-5-1-2-6-10-41(40)44)13-19-70-33-39(56-48(59)37-72-38-49(60)61)34-71-20-14-47(58)53-16-22-65-26-30-69-32-28-67-24-18-55-51(63)74-36-45-42-11-7-3-4-8-12-43(42)45/h39-45H,5-38H2,(H,52,57)(H,53,58)(H,54,62)(H,55,63)(H,56,59)(H,60,61)/t40-,41+,42-,43+,44+,45+
SMILES Code: [H][C@@]12[C@@]([C@@H]2COC(NCCOCCOCCOCCNC(CCOCC(NC(COCC(O)=O)=O)COCCC(NCCOCCOCCOCCNC(OC[C@H]3[C@]4([H])CCC#CCC[C@@]43[H])=O)=O)=O)=O)([H])CCC#CCC1
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 1052.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
