WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 208557
CAS#: 73243-68-2
Description: The effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin (ppDNM) on the lectin binding to HIV-1 glycoprotein was analyzed by using biotinylated lectins of various sugar specificities as probes. ppDNM potentially inhibited HIV-1-induced syncytium formation and viral infectivity of HIV-1 without cytotoxicity. The lectin binding assay showed that ppDNM treatment reduced Con A binding to gp120 of HIV-1.
MedKoo Cat#: 208557
Name: N-(3-Phenyl-2-propenyl)-1-deoxynojirimycin
CAS#: 73243-68-2
Chemical Formula: C15H21NO4
Exact Mass: 279.1471
Molecular Weight: 279.34
Elemental Analysis: C, 64.50; H, 7.58; N, 5.01; O, 22.91
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Synonym: N-(3-Phenyl-2-propenyl)-1-deoxynojirimycin, D-Glucitol
IUPAC/Chemical Name: (2R,3R,4R,5S)-1-cinnamyl-2-(hydroxymethyl)piperidine-3,4,5-trio
InChi Key: NNWNPDDADBLYNP-VHAFJGENSA-N
InChi Code: InChI=1S/C15H21NO4/c17-10-12-14(19)15(20)13(18)9-16(12)8-4-7-11-5-2-1-3-6-11/h1-7,12-15,17-20H,8-10H2/b7-4+/t12-,13+,14-,15-/m1/s1
SMILES Code: O[C@H]1[C@H](O)[C@@H](CO)N(C/C=C/C2=CC=CC=C2)C[C@@H]1O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 279.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Shimizu H, Tsuchie H, Honma H, Yoshida K, Tsuruoka T, Ushijima H, Kitamura T. Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins. Jpn J Med Sci Biol. 1990 Jun;43(3):75-87. doi: 10.7883/yoken1952.43.75. PMID: 2283726.
