WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 121073

CAS#: 2639957-39-2

Description: Exarafenib, also known as KIN-2787. is an antineoplastic. Exarafenib has anticancer activity by suppression of downstream MAPK pathway signaling. Exarafenib can be used for cancer research

Chemical Structure

CAS# 2639957-39-2

Theoretical Analysis

MedKoo Cat#: 121073
Name: Exarafenib
CAS#: 2639957-39-2
Chemical Formula: C26H34F3N5O3
Exact Mass: 521.2614
Molecular Weight: 521.59
Elemental Analysis: C, 59.87; H, 6.57; F, 10.93; N, 13.43; O, 9.20

Price and Availability

Size Price Availability Quantity
5.0mg USD 450.0 2 Weeks
10.0mg USD 750.0 2 Weeks
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Synonym: Exarafenib, RAF/KIN_2787; KIN-2787; KIN 2787; KIN2787;

IUPAC/Chemical Name: (3S)-N-{3-[2-{[(2R)-1-hydroxypropan-2-yl]amino}-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-3-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide


InChi Code: InChI=1S/C26H34F3N5O3/c1-17-3-4-21(31-25(36)34-6-5-19(15-34)14-26(27,28)29)13-22(17)20-11-23(30-18(2)16-35)32-24(12-20)33-7-9-37-10-8-33/h3-4,11-13,18-19,35H,5-10,14-16H2,1-2H3,(H,30,32)(H,31,36)/t18-,19+/m1/s1

SMILES Code: O=C(N1CC[C@@H](CC(F)(F)F)C1)NC2=CC(C3=CC(N[C@H](C)CO)=NC(N4CCOCC4)=C3)=C(C)C=C2

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 521.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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