H-7 inhibitor
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556149

CAS#: 84477-87-2

Description: H-7 is a specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.


Chemical Structure

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H-7 inhibitor
CAS# 84477-87-2

Theoretical Analysis

MedKoo Cat#: 556149
Name: H-7 inhibitor
CAS#: 84477-87-2
Chemical Formula: C14H17N3O2S
Exact Mass: 291.1041
Molecular Weight: 291.369
Elemental Analysis: C, 57.71; H, 5.88; N, 14.42; O, 10.98; S, 11.00

Price and Availability

Size Price Availability Quantity
50.0mg USD 950.0 2 Weeks
100.0mg USD 1450.0 2 Weeks
200.0mg USD 2450.0 2 Weeks
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Synonym: H-7 inhibitor

IUPAC/Chemical Name: 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine

InChi Key: BDVFVCGFMNCYPV-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H17N3O2S/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14/h2-6,10-11,16H,7-9H2,1H3

SMILES Code: CC1N(S(=O)(C2=CC=CC3=C2C=CN=C3)=O)CCNC1

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 291.369 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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