WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 2446148
CAS#: 205254-94-0
Description: GTPL6019, also know nas IUN54940, DGFR Tyrosine Kinase Inhibitor III, is a PDGFR inhibitor with potential anticancer activity.
MedKoo Cat#: 2446148
Name: GTPL-6019
CAS#: 205254-94-0
Chemical Formula: C27H27N5O4
Exact Mass: 485.2063
Molecular Weight: 485.544
Elemental Analysis: C, 66.79; H, 5.61; N, 14.42; O, 13.18
Synonym: PDGFR Tyrosine Kinase Inhibitor III; IUN54940; IUN-54940; IUN 54940; GTPL-6019; GTPL6019; GTPL6019;
IUPAC/Chemical Name: 4-(6,7-Dimethoxy-4-quinazolinyl)-N-(4-phenoxyphenyl)-1-piperazinecarboxamide
InChi Key: INTPTKHSGKBHHW-UHFFFAOYSA-N
InChi Code: InChI=1S/C27H27N5O4/c1-34-24-16-22-23(17-25(24)35-2)28-18-29-26(22)31-12-14-32(15-13-31)27(33)30-19-8-10-21(11-9-19)36-20-6-4-3-5-7-20/h3-11,16-18H,12-15H2,1-2H3,(H,30,33)
SMILES Code: O=C(N1CCN(C2=C3C=C(OC)C(OC)=CC3=NC=N2)CC1)NC4=CC=C(OC5=CC=CC=C5)C=C4
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 485.544 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
