BMS-905
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MedKoo CAT#: 556120

CAS#: 2205846-49-5

Description: BMS-905 is a Dual Antagonist of Toll-like Receptors 7 and 8 (TLR7/8)


Chemical Structure

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BMS-905
CAS# 2205846-49-5

Theoretical Analysis

MedKoo Cat#: 556120
Name: BMS-905
CAS#: 2205846-49-5
Chemical Formula: C23H29N3
Exact Mass: 347.2361
Molecular Weight: 347.506
Elemental Analysis: C, 79.50; H, 8.41; N, 12.09

Price and Availability

Size Price Availability Quantity
50.0mg USD 1450.0 2 Weeks
100.0mg USD 2050.0 2 Weeks
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Synonym: BMS-905; BMS 905; BMS905;

IUPAC/Chemical Name: 2-(2,6-Dimethylpyridin-4-yl)-5-piperidin-4-yl-3-propan-2-yl-1H-indole

InChi Key: XSXCQWXAFRASGU-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H29N3/c1-14(2)22-20-13-18(17-7-9-24-10-8-17)5-6-21(20)26-23(22)19-11-15(3)25-16(4)12-19/h5-6,11-14,17,24,26H,7-10H2,1-4H3

SMILES Code: CC(C1=C(C2=CC(C)=NC(C)=C2)NC3=C1C=C(C4CCNCC4)C=C3)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 347.506 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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Sreekantha RK, Mussari CP, Dodd DS, Pasunoori L, Hegde S, Posy SL, Critton D, Ruepp S, Subramanian M, Salter-Cid LM, Tagore DM, Sarodaya S, Dudhgaonkar S, Poss MA, Schieven GL, Carter PH, Macor JE, Dyckman AJ. Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8). ACS Med Chem Lett. 2022 Apr 25;13(5):812-818. doi: 10.1021/acsmedchemlett.2c00049. PMID: 35586440; PMCID: PMC9109266.

BMS-905

50.0mg / USD 1450.0