SR15006
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556115

CAS#: 2505001-54-5

Description: SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) . SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. SR18662 significantly reduces growth and proliferation of colorectal cancer cells as compared with treatment with vehicle control, SR18662 showed improved efficacy in reducing the viability of multiple colorectal cancer cell lines. SR18662 treatment also reduces the expression of cyclins and components of the MAPK and WNT signaling pathways.


Chemical Structure

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SR15006
CAS# 2505001-54-5

Theoretical Analysis

MedKoo Cat#: 556115
Name: SR15006
CAS#: 2505001-54-5
Chemical Formula: C16H20ClN3O4S
Exact Mass: 385.0863
Molecular Weight: 385.863
Elemental Analysis: C, 49.80; H, 5.22; Cl, 9.19; N, 10.89; O, 16.59; S, 8.31

Price and Availability

Size Price Availability Quantity
50.0mg USD 750.0 2 Weeks
100.0mg USD 1250.0 2 Weeks
200.0mg USD 2050.0 2 Weeks
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Synonym: SR15006; SR-15006; SR 15006

IUPAC/Chemical Name: (E)-3-(3-chlorophenyl)-N-(2-(4-(methylsulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide

InChi Key: DURMLOBZTVQDGQ-AATRIKPKSA-N

InChi Code: InChI=1S/C16H20ClN3O4S/c1-25(23,24)20-9-7-19(8-10-20)16(22)12-18-15(21)6-5-13-3-2-4-14(17)11-13/h2-6,11H,7-10,12H2,1H3,(H,18,21)/b6-5+

SMILES Code: O=C(NCC(N1CCN(S(=O)(C)=O)CC1)=O)/C=C/C2=CC=CC(Cl)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 385.863 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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SR15006

50.0mg / USD 750.0