WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 556114
Description: LUN04765, also known as CCR8 antagonist 1 is a CCR8 antagonist. LUN04765 was first reported in J Med Chem. 2007;50(3):566-584 (compound 15). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 556114
Chemical Formula: C26H29N3O5S
Exact Mass: 495.1828
Molecular Weight: 495.594
Elemental Analysis: C, 63.01; H, 5.90; N, 8.48; O, 16.14; S, 6.47
Synonym: CCR8 antagonist 1; LUN04765; LUN-04765; LUN 04765;
IUPAC/Chemical Name: ethyl 4-((4-(2-methylbenzamido)naphthalene)-1-sulfonamido)piperidine-1-carboxylate
InChi Key: LGJRRERRFSZFTJ-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H29N3O5S/c1-3-34-26(31)29-16-14-19(15-17-29)28-35(32,33)24-13-12-23(21-10-6-7-11-22(21)24)27-25(30)20-9-5-4-8-18(20)2/h4-13,19,28H,3,14-17H2,1-2H3,(H,27,30)
SMILES Code: O=C(N1CCC(NS(=O)(C2=C3C=CC=CC3=C(NC(C4=CC=CC=C4C)=O)C=C2)=O)CC1)OCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 495.594 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
Jenkins TJ, et al. Design, synthesis, and evaluation of naphthalene-sulfonamide antagonists of human CCR8. J Med Chem. 2007;50(3):566-584.