SRI-37330 free base
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MedKoo CAT#: 471191

CAS#: 2322245-42-9 (free base)

Description: SRI-37330 is a novel inhibitor of TXNIP expression, decreasing glucagon secretion and action and blocking hepatic glucose output, reversing obesity- and STZ-induced diabetes and hepatic steatosis.


Chemical Structure

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SRI-37330 free base
CAS# 2322245-42-9 (free base)

Theoretical Analysis

MedKoo Cat#: 471191
Name: SRI-37330 free base
CAS#: 2322245-42-9 (free base)
Chemical Formula: C16H19F3N4O2S
Exact Mass: 388.118
Molecular Weight: 388.409
Elemental Analysis: C, 49.48; H, 4.93; F, 14.67; N, 14.42; O, 8.24; S, 8.25

Price and Availability

Size Price Availability Quantity
1.0mg USD 80.0 Ready to ship
5.0mg USD 150.0 Ready to ship
10.0mg USD 250.0 Ready to ship
25.0mg USD 550.0 Ready to ship
50.0mg USD 950.0 Ready to ship
100.0mg USD 1650.0 Ready to ship
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Related CAS #: 2322245-49-6 (HCl)   2322245-42-9 (free base)    

Synonym: SRI-37330 free base; SRI37330 free base, SRI 37330 free base

IUPAC/Chemical Name: N-((1-(6-(trifluoromethyl)quinazolin-4-yl)piperidin-3-yl)methyl)methanesulfonamide

InChi Key: WRSNFEVXRKOMLL-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H19F3N4O2S/c1-26(24,25)22-8-11-3-2-6-23(9-11)15-13-7-12(16(17,18)19)4-5-14(13)20-10-21-15/h4-5,7,10-11,22H,2-3,6,8-9H2,1H3

SMILES Code: CS(=O)(NCC1CN(C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)CCC1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 388.409 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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