WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 112134
CAS#: 1563007-08-8
Description: G244-LM is an inhibitor of Wnt signaling.
MedKoo Cat#: 112134
Name: G244-LM
CAS#: 1563007-08-8
Chemical Formula: C18H22N4O3S2
Exact Mass: 406.1133
Molecular Weight: 406.52
Elemental Analysis: C, 53.18; H, 5.46; N, 13.78; O, 11.81; S, 15.77
Synonym: G244-LM
IUPAC/Chemical Name: 2-(4-(2-(methylsulfonyl)phenyl)piperazin-1-yl)-1,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one
InChi Key: JSQPAEVPPSCQMV-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H22N4O3S2/c1-27(24,25)16-5-3-2-4-15(16)21-7-9-22(10-8-21)18-19-14-6-11-26-12-13(14)17(23)20-18/h2-5H,6-12H2,1H3,(H,19,20,23)
SMILES Code: O=C1N=C(NC2=C1CSCC2)N3CCN(CC3)C4=C(C=CC=C4)S(C)(=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 2.0 | 4.92 | |
| DMSO | 5.0 | 12.3 | |
| Ethanol | 0.25 | 0.615 |
The following data is based on the product molecular weight 406.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
