Nitrocaramiphen HCl
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MedKoo CAT#: 556106

CAS#: 98636-73-8 (HCl)

Description: Nitrocaramiphen is a muscarinic antagonist with 71-fold selectivity for M1 over M2.


Chemical Structure

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Nitrocaramiphen HCl
CAS# 98636-73-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 556106
Name: Nitrocaramiphen HCl
CAS#: 98636-73-8 (HCl)
Chemical Formula: C18H27ClN2O4
Exact Mass:
Molecular Weight: 370.874
Elemental Analysis: C, 58.29; H, 7.34; Cl, 9.56; N, 7.55; O, 17.26

Price and Availability

Size Price Availability Quantity
50.0mg USD 550.0 2 Weeks
100.0mg USD 950.0 2 Weeks
200.0mg USD 1450.0 2 Weeks
500.0mg USD 2450.0 2 Weeks
1.0g USD 3450.0 2 Weeks
2.0g USD 5950.0 2 Weeks
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Related CAS #: 98636-73-8 (HCl)   135569-16-3 (free base)    

Synonym: Nitrocaramiphen HCl; Nitrocaramiphen hydrochloride; Nitrocaramiphen;

IUPAC/Chemical Name: 2-Diethylaminoethyl 1-(4-nitrophenyl)cyclopentanecarboxylate hydrochloride

InChi Key: XWQWACGTGFICFO-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H26N2O4.ClH/c1-3-19(4-2)13-14-24-17(21)18(11-5-6-12-18)15-7-9-16(10-8-15)20(22)23;/h7-10H,3-6,11-14H2,1-2H3;1H

SMILES Code: O=C(C1(C2=CC=C([N+]([O-])=O)C=C2)CCCC1)OCCN(CC)CC.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 370.874 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Naumenko NV, Malomuzh AI, Khairova RA, Zefirov AL, Urazaev AKh. Farmakologicheskie osobennosti muskarinovykh cholinoretseptorov skeletnykh myshts [Pharmacological parameters of muscarinic cholinoreceptors in skeletal muscles]. Ross Fiziol Zh Im I M Sechenova. 2002 May;88(5):619-26. Russian. PMID: 12136730.

2: Reaper CM, Fanelli F, Buckingham SD, Millar NS, Sattelle DB. Antagonist profile and molecular dynamic simulation of a Drosophila melanogaster muscarinic acetylcholine receptor. Recept Channels. 1998;5(6):331-45. PMID: 9826910.

3: Hudkins RL, Stubbins JF, DeHaven-Hudkins DL. Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarinic M1 receptor-selective agents. Eur J Pharmacol. 1993 Feb 16;231(3):485-8. doi: 10.1016/0014-2999(93)90130-a. PMID: 8449241.

4: Hudkins RL, DeHaven-Hudkins DL. M1 muscarinic antagonists interact with sigma recognition sites. Life Sci. 1991;49(17):1229-35. doi: 10.1016/0024-3205(91)90135-x. Erratum in: Life Sci 1992;50(3):245. PMID: 1658507.