WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556096

CAS#: 2290660-61-4

Description: BDP-13176 is a potent fascin 1 inhibitor. The Kd is 90 nM and the IC50 is 240 nM. BDP-13176 has potential as an anti-metastatic agent.

Chemical Structure

CAS# 2290660-61-4

Theoretical Analysis

MedKoo Cat#: 556096
Name: BDP-13176
CAS#: 2290660-61-4
Chemical Formula: C24H22Cl2N6O2
Exact Mass: 496.1181
Molecular Weight: 497.38
Elemental Analysis: C, 57.96; H, 4.46; Cl, 14.25; N, 16.90; O, 6.43

Price and Availability

Size Price Availability Quantity
25.0mg USD 550.0 2 Weeks
50.0mg USD 950.0 2 Weeks
100.0mg USD 1650.0 2 Weeks
200.0mg USD 2650.0 2 Weeks
500.0mg USD 3950.0 2 Weeks
1.0g USD 4950.0 2 Weeks
2.0g USD 7450.0 2 Weeks
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Synonym: BDP-13176; BDP 13176; BDP13176;

IUPAC/Chemical Name: 5-[(3,4-dichlorophenyl)methyl]-4-oxo-1-piperidin-4-yl-N-pyridin-4-ylpyrazolo[4,3-c]pyridine-7-carboxamide


InChi Code: InChI=1S/C24H22Cl2N6O2/c25-20-2-1-15(11-21(20)26)13-31-14-19(23(33)30-16-3-7-27-8-4-16)22-18(24(31)34)12-29-32(22)17-5-9-28-10-6-17/h1-4,7-8,11-12,14,17,28H,5-6,9-10,13H2,(H,27,30,33)

SMILES Code: O=C(C1=CN(CC2=CC=C(Cl)C(Cl)=C2)C(C3=C1N(C4CCNCC4)N=C3)=O)NC5=CC=NC=C5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 497.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Additional Information

Fascin 1 (fascin) is an actin-bundling protein. It cross-links filamentous actin (F-actin) into tightly packed parallel bundles driving the formation of various cell surface protrusions, such as filopodia and invadopodia. They promote cell migration and invasion. Fascin 1 is either absent or shows low expression in normal epithelial tissues but shows overexpression in a number of cancers, with expression levels correlating with overall cancer aggressiveness and predicting poor clinical outcome. In a word, fascin is an actin-binding and bundling protein. It is not expressed in normal epithelial tissues but overexpressed in a variety of invasive epithelial tumors. It has a critical role in cancer cell metastasis by promoting cell migration and invasion.