WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 112053

CAS#: 6136-37-4

Description: 1-Methylxanthine is an active metabolite of caffeine and enhances ionizing radiation-induced DNA double-strand break formation in RKO colorectal cancer cells when used at a concentration of 3 mM.

Chemical Structure

CAS# 6136-37-4

Theoretical Analysis

MedKoo Cat#: 112053
Name: 1-Methylxanthine
CAS#: 6136-37-4
Chemical Formula: C6H6N4O2
Exact Mass: 166.0491
Molecular Weight: 166.14
Elemental Analysis: C, 43.38; H, 3.64; N, 33.72; O, 19.26

Price and Availability

Size Price Availability Quantity
50.0mg USD 270.0 2 Weeks
100.0mg USD 540.0 2 Weeks
500.0mg USD 1150.0 2 Weeks
1.0g USD 1560.0 2 Weeks
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Synonym: 1-MTX; 1-MX; 1MTX; 1MX; 1 MTX; 1 MX; 1-Methylxanthine; 1Methylxanthine; 1 Methylxanthine

IUPAC/Chemical Name: 1-methyl-3,7-dihydro-1H-purine-2,6-dione


InChi Code: InChI=1S/C6H6N4O2/c1-10-5(11)3-4(8-2-7-3)9-6(10)12/h2H,1H3,(H,7,8)(H,9,12)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 166.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Youn H, Hee Kook Y, Oh ET, Jeong SY, Kim C, Kyung Choi E, Uk Lim B, Park HJ. 1-Methylxanthine enhances the radiosensitivity of tumor cells. Int J Radiat Biol. 2009 Feb;85(2):167-74. doi: 10.1080/09553000902741190. PMID: 19280470.