WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556087

CAS#: 732973-87-4

Description: VUN73874, also known as GOT1 inhibitor 2c, is a glutamate-​oxaloacetate transaminase 1 (GOT1)​ inhibitor. This compound was first reported in Bioorg Med Chem Lett. 2018 Sep 1;28(16):2675-2678. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page:

Chemical Structure

CAS# 732973-87-4

Theoretical Analysis

MedKoo Cat#: 556087
Name: VUN73874
CAS#: 732973-87-4
Chemical Formula: C19H19ClN4O
Exact Mass: 354.1247
Molecular Weight: 354.838
Elemental Analysis: C, 64.31; H, 5.40; Cl, 9.99; N, 15.79; O, 4.51

Price and Availability

Size Price Availability Quantity
200.0mg USD 1950.0 2 Weeks
500.0mg USD 2950.0 2 Weeks
1.0g USD 3950.0 2 Weeks
2.0g USD 6950.0 2 Weeks
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Synonym: GOT1 inhibitor 2c; VUN73874; VUN-73874; VUN 73874;

IUPAC/Chemical Name: N-(4-Chlorophenyl)-4-(1H-indol-4-yl)piperazine-1-carboxamide


InChi Code: InChI=1S/C19H19ClN4O/c20-14-4-6-15(7-5-14)22-19(25)24-12-10-23(11-13-24)18-3-1-2-17-16(18)8-9-21-17/h1-9,21H,10-13H2,(H,22,25)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 354.838 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Anglin J, Zavareh RB, Sander PN, Haldar D, Mullarky E, Cantley LC, Kimmelman AC, Lyssiotis CA, Lairson LL. Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma. Bioorg Med Chem Lett. 2018 Sep 1;28(16):2675-2678. doi: 10.1016/j.bmcl.2018.04.061. Epub 2018 Apr 27. PMID: 29731362; PMCID: PMC6119644.


200.0mg / USD 1950.0