WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 408173
CAS#: 133120-90-8 (TFA)
Description: Dov-Val-Dil-OH is a useful chemical intermediate for synthesis of auristatin-related compounds, such as Monomethyl auristatin E (MMAE), Auristatins are antimitotic agents which inhibits cell division by blocking the polymerisation of tubulin.
MedKoo Cat#: 408173
Name: Dov-Val-Dil-OH TFA
CAS#: 133120-90-8 (TFA)
Chemical Formula: C24H44F3N3O7
Exact Mass:
Molecular Weight: 543.6252
Elemental Analysis: C, 53.03; H, 8.16; F, 10.48; N, 7.73; O, 20.60
Related CAS #: 133120-89-5 (free base) 133120-90-8 (TFA) 2247145-33-9 (HCl)
Synonym: Dov-Val-Dil-OH TFA; Dov-Val-Dil-OH; Dov-Val-Dil-OH; dimethylVal-Val-Dil-COOH;
IUPAC/Chemical Name: (3R,4S,5S)-4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoic acid trifluoroacetic acid
InChi Key: QUIQWXWGYURKKL-NKPYJPHDSA-N
InChi Code: InChI=1S/C22H43N3O5.C2HF3O2/c1-11-15(6)20(16(30-10)12-17(26)27)25(9)22(29)18(13(2)3)23-21(28)19(14(4)5)24(7)8;3-2(4,5)1(6)7/h13-16,18-20H,11-12H2,1-10H3,(H,23,28)(H,26,27);(H,6,7)/t15-,16+,18-,19-,20-;/m0./s1
SMILES Code: CC[C@H](C)[C@H](N(C)C([C@@H](NC([C@@H](N(C)C)C(C)C)=O)C(C)C)=O)[C@H](OC)CC(O)=O.O=C(O)C(F)(F)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 543.6252 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
