WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 466148

CAS#: 1309784-09-5

Description: JTE-051 is a novel inhibitor of interleukin-2-inducible T cell kinase (ITK), suppressing the signal to activate T cells related to immune response.

Chemical Structure

CAS# 1309784-09-5

Theoretical Analysis

MedKoo Cat#: 466148
Name: JTE-051
CAS#: 1309784-09-5
Chemical Formula: C25H33N5O2
Exact Mass: 435.26
Molecular Weight: 435.572
Elemental Analysis: C, 68.94; H, 7.64; N, 16.08; O, 7.35

Price and Availability

Size Price Availability Quantity
10mg USD 450 Ready to ship
25mg USD 850 Ready to ship
50mg USD 1450 Ready to ship
100mg USD 2450 Ready to ship
1mg USD 90 Ready to ship
5mg USD 250 Ready to ship
200mg USD 3650 Ready to ship
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Synonym: JTE-051; JTE051; JTE 051;

IUPAC/Chemical Name: (S)-N-(2-(6,6-dimethyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)-1H-indol-6-yl)-N-methyl-2-morpholinopropanamide


InChi Code: InChI=1S/C25H33N5O2/c1-16(30-9-11-32-12-10-30)24(31)29(4)18-6-5-17-13-21(26-20(17)14-18)23-19-7-8-25(2,3)15-22(19)27-28-23/h5-6,13-14,16,26H,7-12,15H2,1-4H3,(H,27,28)/t16-/m0/s1

SMILES Code: C[C@H](N1CCOCC1)C(N(C2=CC3=C(C=C2)C=C(C4=NNC5=C4CCC(C)(C)C5)N3)C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:
Biological target: JTE-051 is a novel inhibitor of interleukin-2-inducible T cell kinase (ITK).
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 435.572000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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