Pyrilutamide
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MedKoo CAT#: 333078

CAS#: 1272719-00-2

Description: Pyrilutamide, also known as KX826, is an androgen receptor (AR) antagonist and a potential first-in-class topical drug for the treatment of androgenetic alopecia (AGA) and acne vulgaris.


Chemical Structure

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Pyrilutamide
CAS# 1272719-00-2

Theoretical Analysis

MedKoo Cat#: 333078
Name: Pyrilutamide
CAS#: 1272719-00-2
Chemical Formula: C21H15F5N4O2S
Exact Mass: 482.08
Molecular Weight: 482.429
Elemental Analysis: C, 52.28; H, 3.13; F, 19.69; N, 11.61; O, 6.63; S, 6.65

Price and Availability

Size Price Availability Quantity
5mg USD 550 2 Weeks
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Synonym: KX826; KX-826; KX 826; Pyrilutamide;

IUPAC/Chemical Name: 4-[3-[4-Cyano-2-fluoro-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide

InChi Key: CGRMNGGGSWLDDC-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H15F5N4O2S/c1-20(2)18(32)29(14-7-4-10(9-27)15(16(14)23)21(24,25)26)19(33)30(20)11-5-6-12(13(22)8-11)17(31)28-3/h4-8H,1-3H3,(H,28,31)

SMILES Code: O=C(NC)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3F)=S)C(C)(C)C2=O)C=C1F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 482.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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