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MedKoo CAT#: 501105

CAS#: 1062368-24-4 (free base)

Description: LDN193189 is a highly potent small molecule BMP inhibitor with IC50 of 5 and 30 nM for ALK2 and ALK3, respectively. LDN193189 also inhibits BMP type I receptors ALK6 (TGFβ1/BMP signaling) and subsequent SMAD phosphorylation.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 90 Same day
25mg USD 150 Same day
50mg USD 250 Same day
100mg USD 450 Same day
200mg USD 750 Same day
500mg USD 1450 Same day
1g USD 2650 Same day
2g USD 4650 Same day
5g USD 6950 Same day
Inquire bulk and customized quantity

Pricing updated 2020-06-03. Prices are subject to change without notice.

LDN-193189, purity > 98%, is in stock. Same day shipping after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 501105
Name: LDN-193189
CAS#: 1062368-24-4 (free base)
Chemical Formula: C25H22N6
Exact Mass: 406.19059
Molecular Weight: 406.48238
Elemental Analysis: C, 73.87; H, 5.46; N, 20.67

Related CAS #: 1062368-24-4 (free base)   1062368-62-0 (HCl)   1435934-00-1 (dihydrochloride)  

Synonym: LDN193189; LDN 193189; LDN-193189; DM-3189; DM 3189; DM3189;

IUPAC/Chemical Name: 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline


InChi Code: InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Safety Data Sheet (SDS):

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information

Related CAS#
1062368-24-4 ( LDN-193189 free base);
1062368-62-0 ( LDN-193189 HCl)
1435934-00-1 ( LDN-193189 dihydrochloride)


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7: Yonezawa T, Lee JW, Hibino A, Asai M, Hojo H, Cha BY, Teruya T, Nagai K, Chung UI, Yagasaki K, Woo JT. Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling. Biochem Biophys Res Commun. 2011 Jun 3;409(2):260-5. Epub 2011 May 6. PubMed PMID: 21570953.

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