Kenpaullone
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406550

CAS#: 142273-20-9

Description: Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC50 values are 0.68, 7.5 and 0.85 μM respectively).

Chemical Structure

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Kenpaullone
CAS# 142273-20-9
Instruction

Theoretical Analysis

MedKoo Cat#: 406550
Name: Kenpaullone
CAS#: 142273-20-9
Chemical Formula: C16H11BrN2O
Exact Mass: 326.01
Molecular Weight: 327.180
Elemental Analysis: C, 58.74; H, 3.39; Br, 24.42; N, 8.56; O, 4.89

Price and Availability

Size Price Availability Quantity
10mg USD 150 Ready to ship
25mg USD 250 Ready to ship
50mg USD 450 Ready to ship
100mg USD 750 Ready to ship
200mg USD 1250 Ready to ship
500mg USD 2850 2 Weeks
1g USD 3950 2 Weeks
2g USD 6450 2 Weeks
Bulk inquiry

Synonym: NSC664704; NSC-664704; NSC 664704; 9-Bromopaullone; 1-azakenpaullone; Kenpaullone

IUPAC/Chemical Name: 9-bromo-7,12-dihydrobenzo[2,3]azepino[4,5-b]indol-6(5H)-one

InChi Key: QQUXFYAWXPMDOE-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20)

SMILES Code: O=C(NC1=CC=CC=C12)CC3=C2NC4=C3C=C(Br)C=C4

Appearance: White to off-white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:         

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 327.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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