MRN73473
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556047

CAS#: 2448173-47-3

Description: MRN73473, also known as Menin-MLL inhibitor 20, is an irreversible menin-MLL interaction inhibitor with antitumor activities. This compound was first reported in patent WO2020142557A1 (compound 6). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).


Chemical Structure

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MRN73473
CAS# 2448173-47-3

Theoretical Analysis

MedKoo Cat#: 556047
Name: MRN73473
CAS#: 2448173-47-3
Chemical Formula: C33H40N8O4
Exact Mass: 612.3173
Molecular Weight: 612.735
Elemental Analysis: C, 64.69; H, 6.58; N, 18.29; O, 10.44

Price and Availability

Size Price Availability Quantity
100.0mg USD 1650.0 2 Weeks
200.0mg USD 2650.0 2 Weeks
500.0mg USD 4250.0 2 Weeks
1.0g USD 5950.0 2 Weeks
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Synonym: Menin-MLL inhibitor 20; MRN73473; MRN-73473; MRN 73473;

IUPAC/Chemical Name: tert-butyl (R)-(1-((2-((4-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl)carbamoyl)pyridin-4-yl)methyl)piperidin-3-yl)carbamate

InChi Key: MPFHTFMFYAODPE-RUZDIDTESA-N

InChi Code: InChI=1S/C33H40N8O4/c1-33(2,3)45-32(43)38-25-5-4-12-40(20-25)19-22-10-11-34-28(17-22)31(42)37-24-8-6-23(7-9-24)27-18-26-29(39-27)35-21-36-30(26)41-13-15-44-16-14-41/h6-11,17-18,21,25H,4-5,12-16,19-20H2,1-3H3,(H,37,42)(H,38,43)(H,35,36,39)/t25-/m1/s1

SMILES Code: O=C(OC(C)(C)C)N[C@H]1CN(CC2=CC(C(NC3=CC=C(C4=CC5=C(N6CCOCC6)N=CN=C5N4)C=C3)=O)=NC=C2)CCC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 612.735 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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MRN73473

100.0mg / USD 1650.0