QPX7831

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 465709

CAS#: unknown

Description: QPX7831 is a β‑Lactamase Inhibitor.

Chemical Structure

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QPX7831
CAS# unknown
Instruction

Theoretical Analysis

MedKoo Cat#: 465709
Name: QPX7831
CAS#: unknown
Chemical Formula: C15H16BFO6
Exact Mass: 322.10
Molecular Weight: 322.095
Elemental Analysis: C, 55.94; H, 5.01; B, 3.36; F, 5.90; O, 29.80

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: QPX7831; QPX 7831; QPX-7831;

IUPAC/Chemical Name: (isobutyryloxy)methyl (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrobenzo[e]cyclopropa[c][1,2]oxaborinine-4-carboxylate

InChi Key: FCXHIXHOQJYLTG-NXEZZACHSA-N

InChi Code: InChI=1S/C15H16BFO6/c1-7(2)14(18)21-6-22-15(19)12-11(17)4-3-8-9-5-10(9)16(20)23-13(8)12/h3-4,7,9-10,20H,5-6H2,1-2H3/t9-,10-/m1/s1

SMILES Code: OB1[C@H](C2)[C@H]2C3=C(C(C(OCOC(C(C)C)=O)=O)=C(F)C=C3)O1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 322.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Reddy KR, Parkinson J, Sabet M, Tarazi Z, Boyer SH, Lomovskaya O, Griffith DC, Hecker SJ, Dudley MN. Selection of QPX7831, an Orally Bioavailable Prodrug of Boronic Acid β-Lactamase Inhibitor QPX7728. J Med Chem. 2021 Nov 24. doi: 10.1021/acs.jmedchem.1c01722. Epub ahead of print. PMID: 34817182.