N-desethyl Amodiaquine HCl
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MedKoo CAT#: 556039

CAS#: 79049-30-2 (HCl)

Description: N-desethyl Amodiaquine is a primary metabolite of the antimalarial compound aminodiaquine, produced by the action of cytochrome P450 isoform 2C8. N-desethyl Amodiaquine is highly active against P. falciparum and can synergize with amodiaquine.


Chemical Structure

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N-desethyl Amodiaquine HCl
CAS# 79049-30-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 556039
Name: N-desethyl Amodiaquine HCl
CAS#: 79049-30-2 (HCl)
Chemical Formula: C18H20Cl3N3O
Exact Mass:
Molecular Weight: 400.728
Elemental Analysis: C, 53.95; H, 5.03; Cl, 26.54; N, 10.49; O, 3.99

Price and Availability

Size Price Availability Quantity
100.0mg USD 550.0 2 Weeks
200.0mg USD 950.0 2 Weeks
500.0mg USD 1650.0 2 Weeks
1.0g USD 2850.0 2 Weeks
2.0g USD 4950.0 2 Weeks
5.0g USD 7950.0 2 Weeks
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Related CAS #: 79049-30-2 (HCl)   79352-78-6 (free base)    

Synonym: N-desethyl Amodiaquine HCl;

IUPAC/Chemical Name: Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(ethylamino)methyl]-, dihydrochloride (9CI)

InChi Key: BCYBRFGUODDEGH-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H18ClN3O.2ClH/c1-2-20-11-12-9-14(4-6-18(12)23)22-16-7-8-21-17-10-13(19)3-5-15(16)17;;/h3-10,20,23H,2,11H2,1H3,(H,21,22);2*1H

SMILES Code: OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CNCC.[H]Cl.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 400.728 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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