CUN79177
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MedKoo CAT#: 556025

CAS#: 2270879-17-7

Description: CUN79177, also known as BRM/BRG1 ATP Inhibitor-1, is an orally Active Inhibitors (IC50=5 nM) of Brahma Homolog (BRM)​/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)​/SMARCA4-​Mutant Cancers. CUN79177 was first reported ion Journal of Medicinal Chemistry (2018), 61(22), 10155-10172. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).


Chemical Structure

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CUN79177
CAS# 2270879-17-7

Theoretical Analysis

MedKoo Cat#: 556025
Name: CUN79177
CAS#: 2270879-17-7
Chemical Formula: C11H9F3N4O2S
Exact Mass: 318.0398
Molecular Weight: 318.2742
Elemental Analysis: C, 41.51; H, 2.85; F, 17.91; N, 17.60; O, 10.05; S, 10.07

Price and Availability

Size Price Availability Quantity
100.0mg USD 2950.0 2 Weeks
200.0mg USD 3950.0 2 Weeks
500.0mg USD 4950.0 2 Weeks
1.0g USD 7950.0 2 Weeks
2.0g USD 13950.0 2 Weeks
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Synonym: BRM/BRG1 ATP Inhibitor-1; CUN79177; CUN79177; CUN-79177;

IUPAC/Chemical Name: 1-[3-(Difluoromethyl)isothiazol-5-yl]-3-[2-fluoro-5-(hydroxymethyl)pyridin-4-yl]urea

InChi Key: CKYCAIAVJIFWPE-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H9F3N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)

SMILES Code: O=C(NC1=CC(F)=NC=C1CO)NC2=CC(C(F)F)=NS2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 318.2742 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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CUN79177

100.0mg / USD 2950.0