WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 464958

CAS#: 183298-68-2

Description: L161240 is an antibacterial agent.

Chemical Structure

CAS# 183298-68-2

Theoretical Analysis

MedKoo Cat#: 464958
Name: L161240
CAS#: 183298-68-2
Chemical Formula: C15H20N2O5
Exact Mass: 308.1372
Molecular Weight: 308.334
Elemental Analysis: C, 58.43; H, 6.54; N, 9.09; O, 25.94

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: L161240; L 161240; L-161240;

IUPAC/Chemical Name: (R)-2-(3,4-dimethoxy-5-propylphenyl)-N-hydroxy-4,5-dihydrooxazole-4-carboxamide


InChi Code: InChI=1S/C15H20N2O5/c1-4-5-9-6-10(7-12(20-2)13(9)21-3)15-16-11(8-22-15)14(18)17-19/h6-7,11,19H,4-5,8H2,1-3H3,(H,17,18)/t11-/m1/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 308.334 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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1: Onishi HR, Pelak BA, Gerckens LS, Silver LL, Kahan FM, Chen MH, Patchett AA, Galloway SM, Hyland SA, Anderson MS, Raetz CR. Antibacterial agents that inhibit lipid A biosynthesis. Science. 1996 Nov 8;274(5289):980-2. doi: 10.1126/science.274.5289.980. PMID: 8875939.

2: Barb AW, Jiang L, Raetz CR, Zhou P. Assignment of 1H, 13C and 15N backbone resonances of Escherichia coli LpxC bound to L-161,240. Biomol NMR Assign. 2010 Apr;4(1):37-40. doi: 10.1007/s12104-009-9201-5. Epub 2009 Nov 26. PMID: 19941092; PMCID: PMC3631426.

3: Lee CJ, Liang X, Gopalaswamy R, Najeeb J, Ark ED, Toone EJ, Zhou P. Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC. ACS Chem Biol. 2014 Jan 17;9(1):237-46. doi: 10.1021/cb400067g. Epub 2013 Oct 31. PMID: 24117400; PMCID: PMC3947053.