WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 577032
Description: Zifrosilone is an acetylcholinesterase inhibitor.
MedKoo Cat#: 577032
Chemical Formula: C11H13F3OSi
Exact Mass: 246.0688
Molecular Weight: 246.3
Elemental Analysis: C, 53.64; H, 5.32; F, 23.14; O, 6.50; Si, 11.40
This product is not in stock, which may be available by custom synthesis.
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Synonym: MDL 73745; MDL-73745; MDL73745; Zifrosilone
IUPAC/Chemical Name: Ethanone, 2,2,2-trifluoro-1-(3-(trimethylsilyl)phenyl)-
InChi Key: GAPOASFZXBWUGS-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H13F3OSi/c1-16(2,3)9-6-4-5-8(7-9)10(15)11(12,13)14/h4-7H,1-3H3
SMILES Code: C[Si](C)(C)c1cccc(c1)C(=O)C(F)(F)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 246.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Cutler NR, Seifert RD, Schleman MM, Sramek JJ, Szylleyko OJ, Howard DR, Barchowsky A, Wardle TS, Brass EP. Acetylcholinesterase inhibition by zifrosilone: pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther. 1995 Jul;58(1):54-61. doi: 10.1016/0009-9236(95)90072-1. PMID: 7628183.