WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 464874
Description: XZ-120312 is a PARP-1 inhibitor with IC50 = 8.6 nM.
MedKoo Cat#: 464874
Chemical Formula: C15H21N5O
Exact Mass: 287.1746
Molecular Weight: 287.367
Elemental Analysis: C, 62.70; H, 7.37; N, 24.37; O, 5.57
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: XZ-120312; XZ120312; XZ 120312;
IUPAC/Chemical Name: 2-(1-propylpiperidin-4-yl)-3H-imidazo[4,5-c]pyridine-7-carboxamide
InChi Key: GXXJUGPFJHOGND-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H21N5O/c1-2-5-20-6-3-10(4-7-20)15-18-12-9-17-8-11(14(16)21)13(12)19-15/h8-10H,2-7H2,1H3,(H2,16,21)(H,18,19)
SMILES Code: O=C(N)C1=C2C(NC(C3CCN(CCC)CC3)=N2)=CN=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 287.367 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Zhu Q, Wang X, Hu Y, He X, Gong G, Xu Y. Discovery and SAR study of 2-(1-propylpiperidin-4-yl)-3H-imidazo[4,5-c]pyridine-7-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1) for the treatment of cancer. Bioorg Med Chem. 2015 Oct 15;23(20):6551-9. doi: 10.1016/j.bmc.2015.09.026. Epub 2015 Sep 16. PMID: 26422786.