YAN7874

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 464866

CAS#: unknown

Description: YAN7874 is a potent orexin agonist (EC50 > 3.2 uM).


Chemical Structure

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YAN7874
CAS# unknown

Theoretical Analysis

MedKoo Cat#: 464866
Name: YAN7874
CAS#: unknown
Chemical Formula: C23H21Cl2N3O
Exact Mass: 425.1062
Molecular Weight: 426.341
Elemental Analysis: C, 64.80; H, 4.97; Cl, 16.63; N, 9.86; O, 3.75

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: YAN7874; YAN 7874; YAN-7874;

IUPAC/Chemical Name: 1-(3,4-dichlorophenyl)-2-(2-imino-3-(4-methylbenzyl)-2,3-dihydro-1H-benzo[d]imidazol-1-yl)ethan-1-ol

InChi Key: LQYDYWMFFKKSFD-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H21Cl2N3O/c1-15-6-8-16(9-7-15)13-27-20-4-2-3-5-21(20)28(23(27)26)14-22(29)17-10-11-18(24)19(25)12-17/h2-12,22,26,29H,13-14H2,1H3

SMILES Code: CC(C=C1)=CC=C1CN(C2=CC=CC=C2N3CC(O)C4=CC(Cl)=C(Cl)C=C4)C3=N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 426.341 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Turku A, Rinne MK, Boije Af Gennäs G, Xhaard H, Lindholm D, Kukkonen JP. Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity. PLoS One. 2017 Jun 2;12(6):e0178526. doi: 10.1371/journal.pone.0178526. PMID: 28575023; PMCID: PMC5456073.