MedKoo Biosciences

Trolamine
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WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 414418

CAS#: 102-71-6

Description: Trolamine is a pain reliever. It is used to treat pain in muscles or joints.

Chemical Structure

Trolamine

CAS# 102-71-6

Instruction

Theoretical Analysis

MedKoo Cat#: 414418
Name: Trolamine
CAS#: 102-71-6
Chemical Formula: C6H15NO3
Exact Mass: 149.11
Molecular Weight: 149.190
Elemental Analysis: C, 48.30; H, 10.13; N, 9.39; O, 32.17

Price and Availability

Size	Price	Availability	Quantity
5mL	USD 309	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: Trolamine; CCRIS606; CCRIS-606; CCRIS 606

IUPAC/Chemical Name: 2,2',2''-nitrilotris(ethan-1-ol)

InChi Key: GSEJCLTVZPLZKY-UHFFFAOYSA-N

InChi Code: InChI=1S/C6H15NO3/c8-4-1-7(2-5-9)3-6-10/h8-10H,1-6H2

SMILES Code: OCCN(CCO)CCO

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Product Data

Instruction:

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 149.190000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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1: Trolamine: over-the-counter. Prescrire Int. 2010 Apr;19(106):64. PMID: 20568679. 2: Del Rosso JQ, Bikowski J. Trolamine-containing topical emulsion: clinical applications in dermatology. Cutis. 2008 Mar;81(3):209-14. PMID: 18441842. 3: Rosenthal A, Israilevich R, Moy R. Management of acute radiation dermatitis: A review of the literature and proposal for treatment algorithm. J Am Acad Dermatol. 2019 Aug;81(2):558-567. doi: 10.1016/j.jaad.2019.02.047. Epub 2019 Feb 22. PMID: 30802561. 4: Menêses AG, Reis PEDD, Guerra ENS, Canto GL, Ferreira EB. Use of trolamine to prevent and treat acute radiation dermatitis: a systematic review and meta- analysis. Rev Lat Am Enfermagem. 2018;26:e2929. doi: 10.1590/1518-8345.2035.2929. Epub 2018 May 7. PMID: 29742271; PMCID: PMC5942864. 5: Lu S, Lu A, Paslin D. A Comparison of the Wound Healing Efficacy of Trolamine Emulsion, Manuka Gel, and Polymyxin-Bacitracin Ointment. Adv Skin Wound Care. 2020 Apr;33(4):217-220. doi: 10.1097/01.ASW.0000655468.08618.fc. PMID: 32195725. 6: Aaron K, Cooper TE, Warner L, Burton MJ. Ear drops for the removal of ear wax. Cochrane Database Syst Rev. 2018 Jul 25;7(7):CD012171. doi: 10.1002/14651858.CD012171.pub2. PMID: 30043448; PMCID: PMC6492540. 7: Kim Y, Beck-Broichsitter M, Banga AK. Design and Evaluation of a Poly(Lactide-co-Glycolide)-Based In Situ Film-Forming System for Topical Delivery of Trolamine Salicylate. Pharmaceutics. 2019 Aug 12;11(8):409. doi: 10.3390/pharmaceutics11080409. PMID: 31408990; PMCID: PMC6723844. 8: Algozzine GJ, Stein GH, Doering PL, Araujo OE, Akin KC. Trolamine salicylate cream in osteoarthritis of the knee. JAMA. 1982 Mar 5;247(9):1311-3. PMID: 7038182. 9: Abbas H, Bensadoun RJ. Trolamine emulsion for the prevention of radiation dermatitis in patients with squamous cell carcinoma of the head and neck. Support Care Cancer. 2012 Jan;20(1):185-90. doi: 10.1007/s00520-011-1110-3. Epub 2011 Feb 22. PMID: 21340657. 10: Tran B, Wu JJ, Ratner D, Han G. Topical Scar Treatment Products for Wounds: A Systematic Review. Dermatol Surg. 2020 Dec;46(12):1564-1571. doi: 10.1097/DSS.0000000000002712. PMID: 32932267.

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