Zomepirac sodium

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MedKoo CAT#: 576936

CAS#: 64092-48-4 (sodium)

Description: Zomepirac sodium anhydrous is a prostaglandin synthetase inhibitor and is not an opioid, an opioid antagonist, or a salicylate.

Chemical Structure

Zomepirac sodium
CAS# 64092-48-4 (sodium)

Theoretical Analysis

MedKoo Cat#: 576936
Name: Zomepirac sodium
CAS#: 64092-48-4 (sodium)
Chemical Formula: C15H13ClNNaO3
Exact Mass: 313.0482
Molecular Weight: 313.71
Elemental Analysis: C, 57.43; H, 4.18; Cl, 11.30; N, 4.46; Na, 7.33; O, 15.30

Price and Availability

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1.0g USD 450.0 2 Weeks
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Related CAS #: 33369-31-2 (free acid)   64092-48-4 (sodium)   64092-49-5 (sodium hydrate)    

Synonym: Sodium zomepirac; Zomax, Zomepirac sodium, Zomepirac sodium anhydrous

IUPAC/Chemical Name: 1H-Pyrrole-2-acetic acid, 5-(4-chlorobenzoyl)-1,4-dimethyl-, sodium salt


InChi Code: InChI=1S/C15H14ClNO3.Na/c1-9-7-12(8-13(18)19)17(2)14(9)15(20)10-3-5-11(16)6-4-10;/h3-7H,8H2,1-2H3,(H,18,19);/q;+1/p-1

SMILES Code: O=C([O-])CC1=CC(C)=C(C(C2=CC=C(Cl)C=C2)=O)N1C.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 313.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. McEvoy GK. Evaluation of zomepirac sodium. Am J Hosp Pharm. 1981 Sep;38(9):1293-301. PMID: 7025615.

2. Muschek LD, Grindel JM. Review of the pharmacokinetics and metabolism of zomepirac in man and animals. J Clin Pharmacol. 1980 Apr;20(4):223-9. doi: 10.1002/j.1552-4604.1980.tb01702.x. PMID: 6769977.

3. McLeod DC. Zomepirac (Zomax, McNeil Pharmaceutical). Drug Intell Clin Pharm. 1981 Jul-Aug;15(7-8):522-30. doi: 10.1177/1060028081015007-802. PMID: 7018870.