WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 414281
Description: L-163491 is a drug which acts as a partial agonist of angiotensin II receptor type 1, and with lower affinity as an agonist of angiotensin II receptor type 2, mimicking the action of angiotensin II. Its practical applications to date have been limited to scientific research into the function of the angiotensin receptor system, but it has been suggested as a potential therapeutic agent for the treatment of inflammation of the lungs associated with certain viral diseases such as COVID-19.
MedKoo Cat#: 414281
Chemical Formula: C36H40N4O5S
Exact Mass: 640.2719
Molecular Weight: 640.79
Elemental Analysis: C, 67.48; H, 6.29; N, 8.74; O, 12.48; S, 5.00
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: L-163491; L163491; L 163491
IUPAC/Chemical Name: 5,7-Dimethyl-2-ethyl-3-((2'-((butyloxycarbonyl) aminosulfonyl)-5'-(3-methyoxybenzyl)-(1,1'-biphenyl)-4-yl)methyl)-3H-imidazo(4,5-b)pyridine
InChi Key: SRCIRAKBWHTYIX-UHFFFAOYSA-N
InChi Code: InChI=1S/C36H40N4O5S/c1-6-8-18-45-36(41)39-46(42,43)32-17-14-28(20-27-10-9-11-30(21-27)44-5)22-31(32)29-15-12-26(13-16-29)23-40-33(7-2)38-34-24(3)19-25(4)37-35(34)40/h9-17,19,21-22H,6-8,18,20,23H2,1-5H3,(H,39,41)
SMILES Code: COC1=CC(CC2=CC=C(S(=O)(NC(OCCCC)=O)=O)C(C3=CC=C(CN4C(CC)=NC5=C(C)C=C(C)N=C54)C=C3)=C2)=CC=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 640.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|