Norbergenin
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MedKoo CAT#: 333059

CAS#: 79595-97-4

Description: Norbergenin, also known as Demethylbergenin, is the O-demethyl derivative of bergenin, the main component of Mallotus japonicus, has been found to show moderate antioxidant activity (IC(50) 13 microM in DPPH radical scavenging; 32 microM in superoxide anion scavenging).


Chemical Structure

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Norbergenin
CAS# 79595-97-4

Theoretical Analysis

MedKoo Cat#: 333059
Name: Norbergenin
CAS#: 79595-97-4
Chemical Formula: C13H14O9
Exact Mass: 314.0638
Molecular Weight: 314.246
Elemental Analysis: C, 49.69; H, 4.49; O, 45.82

Price and Availability

Size Price Availability Quantity
50.0mg USD 1350.0 2 Weeks
100.0mg USD 1950.0 2 Weeks
200.0mg USD 2950.0 2 Weeks
500.0mg USD 3950.0 2 Weeks
1.0g USD 5950.0 2 Weeks
2.0g USD 8950.0 2 Weeks
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Synonym: Norbergenin; Demethylbergenin,

IUPAC/Chemical Name: Pyrano(3,2-c)(2)benzopyran-6(2H)-one, 3,4,4a,10b-tetrahydro-3,4,8,9,10-pentahydroxy-2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,4aalpha,10bbeta))-

InChi Key: GDYGAIKPBLFCKR-OIPGZRGRSA-N

InChi Code: InChI=1S/C13H14O9/c14-2-5-8(17)10(19)12-11(21-5)6-3(13(20)22-12)1-4(15)7(16)9(6)18/h1,5,8,10-12,14-19H,2H2/t5-,8-,10+,11+,12-/m1/s1

SMILES Code: O=C1C2=CC(O)=C(O)C(O)=C2[C@@]3([H])[C@]([C@@H](O)[C@H](O)[C@@H](CO)O3)([H])O1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 314.246 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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20: Kashima Y, Miyazawa M. Synthesis, antioxidant capacity, and structure- activity relationships of tri-O-methylnorbergenin analogues on tyrosinase inhibition. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6580-4. doi: 10.1016/j.bmcl.2013.10.066. Epub 2013 Nov 7. PMID: 24268551.