NA 0346

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 110220

CAS#: 120925-61-3

Description: NA 0346 is a derivative of SF 2370 that shows long lasting antihypertensive action as well as potent protein kinases inhibitory activity.

Chemical Structure

NA 0346
CAS# 120925-61-3

Theoretical Analysis

MedKoo Cat#: 110220
Name: NA 0346
CAS#: 120925-61-3
Chemical Formula: C26H22N4O3
Exact Mass: 438.1692
Molecular Weight: 438.49
Elemental Analysis: C, 71.22; H, 5.06; N, 12.78; O, 10.95

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: NA 0346; NA0346; NA-0346

IUPAC/Chemical Name: 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocin-1-one, 10-(aminomethyl)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-, (9S-(9alpha,10beta,12alpha))-


InChi Code: InChI=1S/C26H22N4O3/c1-25-26(32,12-27)10-18(33-25)29-16-8-4-2-6-13(16)20-21-15(11-28-24(21)31)19-14-7-3-5-9-17(14)30(25)23(19)22(20)29/h2-9,18,32H,10-12,27H2,1H3,(H,28,31)/t18-,25+,26+/m1/s1

SMILES Code: C[C@]12[C@](CN)(O)C[C@](O2)([H])N3C4=CC=CC=C4C5=C6C(CN=C6O)=C7C8=CC=CC=C8N1C7=C53

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 438.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Hachisu M, Hiranuma T, Koyama M, Sezaki M. Antihypertensive compounds with potent protein kinases inhibitory activity. Life Sci. 1989;44(19):1351-62. doi: 10.1016/0024-3205(89)90392-5. PMID: 2765030.