Ibopamine hydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576698

CAS#: 75011-65-3

Description: Ibopamine hydrochloride is a sympathomimetic drug designed as a prodrug of epinine and used in ophthalmology. It induces mydriasis -- dilation of the pupil of the eye..

Chemical Structure

Ibopamine hydrochloride
CAS# 75011-65-3

Theoretical Analysis

MedKoo Cat#: 576698
Name: Ibopamine hydrochloride
CAS#: 75011-65-3
Chemical Formula: C17H26ClNO4
Exact Mass: 343.155
Molecular Weight: 343.85
Elemental Analysis: C, 59.38; H, 7.62; Cl, 10.31; N, 4.07; O, 18.61

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Ibopamine hydrochloride; Ibopamine HCl; Inopamil hydrochloride; Inopamil HCl; SB 7505; SB7505; SB-7505

IUPAC/Chemical Name: Propanoic acid, 2-methyl-, 4-(2-(methylamino)ethyl)-1,2-phenylene ester, hydrochloride


InChi Code: InChI=1S/C17H25NO4.ClH/c1-11(2)16(19)21-14-7-6-13(8-9-18-5)10-15(14)22-17(20)12(3)4;/h6-7,10-12,18H,8-9H2,1-5H3;1H

SMILES Code: Cl.CNCCc1ccc(OC(=O)C(C)C)c(OC(=O)C(C)C)c1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 343.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Landers J, Ullrich K, Craig JE. Ibopamine challenge testing differentiates glaucoma suspect, stable glaucoma and progressive glaucoma cases. Clin Exp Ophthalmol. 2015 Dec;43(9):808-14. doi: 10.1111/ceo.12569. Epub 2015 Jul 27. PubMed PMID: 26140527.

2: Landers J, Ullrich K, Craig JE. Ibopamine challenge testing becomes negative following successful trabeculectomy surgery. Clin Exp Ophthalmol. 2016 Apr;44(3):166-9. doi: 10.1111/ceo.12684. Epub 2016 Feb 12. PubMed PMID: 26575026.

3: Domínguez-Dueñas F, Plaza-Espinosa L, Mundo-Fernández EE, Jiménez-Reynoso CA, Barojas-Weber E, Barrientos-Gutiérrez T. Early Glaucoma Screening Using the Ibopamine Provocative Test. J Glaucoma. 2016 May;25(5):e441-5. doi: 10.1097/IJG.0000000000000343. PubMed PMID: 26709501.

4: Ullrich K, Craig JE, Landers J. Ibopamine challenge test can be used to differentiate glaucoma suspects from glaucoma patients. Clin Exp Ophthalmol. 2014 May-Jun;42(4):342-6. doi: 10.1111/ceo.12200. Epub 2013 Oct 8. PubMed PMID: 24034130.

5: Virno M, Sampaolesi R, Pecori Giraldi J, De Gregorio F, Taloni M, Brusini P, Di Staso S, Stecchi G. Ibopamine: D1-dopaminergic agonist in the diagnosis of glaucoma. J Glaucoma. 2013 Jan;22(1):5-9. doi: 10.1097/IJG.0b013e3182311db4. PubMed PMID: 21946546.