WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 555972
Description: CAY10698 is an inhibitor of 12-LO with an IC50 value of 5.1 µM.
MedKoo Cat#: 555972
Chemical Formula: C17H17N3O4S2
Exact Mass: 391.066
Molecular Weight: 391.46
Elemental Analysis: C, 52.16; H, 4.38; N, 10.73; O, 16.35; S, 16.38
Synonym: CAY10698; CAY-10698; CAY 10698;
IUPAC/Chemical Name: 4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-N-2-thiazolyl-benzenesulfonamide
InChi Key: CENSVXZQMJBVHY-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H17N3O4S2/c1-24-15-4-2-3-12(16(15)21)11-19-13-5-7-14(8-6-13)26(22,23)20-17-18-9-10-25-17/h2-10,19,21H,11H2,1H3,(H,18,20)
SMILES Code: O=S(C1=CC=C(NCC2=CC=CC(OC)=C2O)C=C1)(NC3=NC=CS3)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
|Solvent||Max Conc. mg/mL||Max Conc. mM|
The following data is based on the product molecular weight 391.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Chen, X.-S., Kurre, U., Jenkins, N.A., et al. cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases. J. Biol. Chem. 269(19), 13979-13987 (1994).
2. Luci, D.K., Jameson, J.B., II, Yasgar, A., et al. Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. Journal of Medicinal Chemistry 57(2), 495-506 (2014).