WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576526

CAS#: 103586-12-5

Description: ICI-190622 is a pyrazolopyridine non-benzodiazepine anxiolytic.

Chemical Structure

CAS# 103586-12-5

Theoretical Analysis

MedKoo Cat#: 576526
Name: ICI-190622
CAS#: 103586-12-5
Chemical Formula: C15H17N5O
Exact Mass: 283.1433
Molecular Weight: 283.33
Elemental Analysis: C, 63.59; H, 6.05; N, 24.72; O, 5.65

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: ICI-190622; ICI190622; ICI 190622

IUPAC/Chemical Name: 1H-Pyrazolo(3,4-b)pyridine-5-carboxamide, 4-amino-1-(3-pentynyl)-N-2-propenyl-


InChi Code: InChI=1S/C15H17N5O/c1-3-5-6-8-20-14-11(10-19-20)13(16)12(9-18-14)15(21)17-7-4-2/h4,9-10H,2,6-8H2,1H3,(H2,16,18)(H,17,21)

SMILES Code: CC#CCCn1ncc2c(N)c(cnc12)C(=O)NCC=C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 283.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Patel JB, Meiners BA, Salama AI, Malick JB, U'Prichard DC, Giles RE, Goldberg ME, Bare TM. Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622. Pharmacol Biochem Behav. 1988 Apr;29(4):775-9. doi: 10.1016/0091-3057(88)90205-5. PMID: 2901116.