WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 464493

CAS#: 605-32-3

Description: 2-Hydroxyanthraquinone is an anthraquinone that has been found in Spermacoce latifolia and has antibacterial and estrogenic activities. It is active against B. subtilis and B. cereus (MICs = 1.9 and 62.5 µg/ml, respectively). 2-Hydroxyanthraquinone (19 µM) induces estrogen receptor α (ERα) activation in a yeast two-hybrid assay.

Chemical Structure

CAS# 605-32-3

Theoretical Analysis

MedKoo Cat#: 464493
Name: 2-hATQ
CAS#: 605-32-3
Chemical Formula: C14H8O3
Exact Mass: 224.0473
Molecular Weight: 224.215
Elemental Analysis: C, 75.00; H, 3.60; O, 21.41

Price and Availability

Size Price Availability Quantity
5.0g USD 250.0 2 Weeks
10.0g USD 450.0 2 Weeks
25.0g USD 950.0 2 Weeks
Bulk inquiry

Synonym: 2-hATQ; 2 hATQ; 2-Hydroxyanthraquinone; 2 Hydroxyanthraquinone; 2-hydroxy-9,10-Anthraquinone; β-Hydroxyanthraquinone; β Hydroxyanthraquinone; NSC 2595; NSC2595; NSC-2595;

IUPAC/Chemical Name: 2-hydroxyanthracene-9,10-dione


InChi Code: InChI=1S/C14H8O3/c15-8-5-6-11-12(7-8)14(17)10-4-2-1-3-9(10)13(11)16/h1-7,15H

SMILES Code: O=C1C2=C(C=CC=C2)C(C3=CC(O)=CC=C13)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
DMF 5.0 22.3
DMSO 30.0 133.8

Preparing Stock Solutions

The following data is based on the product molecular weight 224.215 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Butterworth BE, Mathre OB, Ballinger KE, Adalsteinsson O. Contamination is a frequent confounding factor in toxicology studies with anthraquinone and related compounds. Int J Toxicol. 2004;23(5):335-44. doi: 10.1080/10915810490517072. PMID: 15513832.

2: Mallakin A, McConkey BJ, Miao G, McKibben B, Snieckus V, Dixon DG, Greenberg BM. Impacts of structural photomodification on the toxicity of environmental contaminants: anthracene photooxidation products. Ecotoxicol Environ Saf. 1999 Jun;43(2):204-12. doi: 10.1006/eesa.1999.1764. PMID: 10375423.

3: Ramamoorthy S, Mudgal G, Rajesh D, Nawaz Khan F, Vijayakumar V, Rajasekaran C. Characterisation of novel pH indicator of natural dye Oldenlandia umbellata L. Nat Prod Res. 2009;23(13):1210-7. doi: 10.1080/14786410802696635. PMID: 19731140.

4: Shi Y, Wang CH, Gong XG. Apoptosis-inducing effects of two anthraquinones from Hedyotis diffusa WILLD. Biol Pharm Bull. 2008 Jun;31(6):1075-8. doi: 10.1248/bpb.31.1075. PMID: 18520033.

5: Tikkanen L, Matsushima T, Natori S. Mutagenicity of anthraquinones in the Salmonella preincubation test. Mutat Res. 1983 Mar;116(3-4):297-304. doi: 10.1016/0165-1218(83)90067-8. PMID: 6339896.

6: Hilgert I, Cudlín J, Steinerová N, Vanĕk Z. Antitumour and immunosuppressive activity of hydroxyanthraquinones and their glucosides. Folia Biol (Praha). 1977;23(2):99-109. PMID: 863051.