ICI-194008

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576496

CAS#: 112606-65-2

Description: ICI-194008 is a semisynthetic aminothiazolyl cephalosporin.


Chemical Structure

img
ICI-194008
CAS# 112606-65-2

Theoretical Analysis

MedKoo Cat#: 576496
Name: ICI-194008
CAS#: 112606-65-2
Chemical Formula: C26H28N8O7S3
Exact Mass: 660.1243
Molecular Weight: 660.74
Elemental Analysis: C, 47.26; H, 4.27; N, 16.96; O, 16.95; S, 14.56

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ICI-194008; ICI 194008; ICI194008

IUPAC/Chemical Name: Thieno(2,3-d)pyrimidinium, 4-(((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)ethylamino)-1-methyl-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-

InChi Key: UTIIUUIQHFQQRL-SEVZJSAHSA-N

InChi Code: InChI=1S/C26H28N8O7S3/c1-5-33(18-13-6-7-42-21(13)32(4)11-28-18)8-12-9-43-22-16(20(36)34(22)17(12)23(37)38)30-19(35)15(14-10-44-25(27)29-14)31-41-26(2,3)24(39)40/h6-7,10-11,16,22H,5,8-9H2,1-4H3,(H4-,27,29,30,35,37,38,39,40)/b31-15+/t16-,22-/m1/s1

SMILES Code: CCN(CC1=C(N2[C@H](SC1)[C@H](NC(=O)\C(=N\OC(C)(C)C(=O)O)\c3csc(N)n3)C2=O)C(=O)[O-])c4nc[n+](C)c5sccc45

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 660.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1. Allan JD Jr, Eliopoulos GM, Reiszner E, Moellering RC Jr. In vitro activities of ICI 194008 and ICI 193428, two new cephem antimicrobial agents. Antimicrob Agents Chemother. 1987 Dec;31(12):1997-2001. doi: 10.1128/aac.31.12.1997. PMID: 3326527; PMCID: PMC175842.

2. García-Rodríguez JA, García Sánchez JE, García García MI, García Sánchez E, Muñoz Bellido JL. Antibiotic susceptibility profile of Xanthomonas maltophilia. In vitro activity of beta-lactam/beta-lactamase inhibitor combinations. Diagn Microbiol Infect Dis. 1991 May-Jun;14(3):239-43. doi: 10.1016/0732-8893(91)90038-h. PMID: 1889176.