WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 555968
CAS#: 2409963-83-1
Description: DWN63831 is a lysyl oxidase inhbitor. DWN63831 may be useful in treatment of a variety of disorders, e.g., fibrosis, cancer and angiogenesis in human subjects as well as in pets and livestock. DWN63831 was first reported in patent WO 2020024017. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
MedKoo Cat#: 555968
Name: DWN63831
CAS#: 2409963-83-1
Chemical Formula: C13H13FN2O2S
Exact Mass: 280.0682
Molecular Weight: 280.3174
Elemental Analysis: C, 55.70; H, 4.67; F, 6.78; N, 9.99; O, 11.41; S, 11.44
Synonym: DWN63831; DWN-63831; DWN 63831;
IUPAC/Chemical Name: (Z)-3-Fluoro-4-(quinolin-8-ylsulfonyl)but-2-en-1-amine
InChi Key: DHXXLGDTPFPYRH-WDZFZDKYSA-N
InChi Code: InChI=1S/C13H13FN2O2S/c14-11(6-7-15)9-19(17,18)12-5-1-3-10-4-2-8-16-13(10)12/h1-6,8H,7,9,15H2/b11-6-
SMILES Code: NC/C=C(F)/CS(=O)(C1=C2N=CC=CC2=CC=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
| Biological target: | LOX-IN-3 is an orally active lysyl oxidase (LOX) inhibitor. |
| In vitro activity: | TBD |
| In vivo activity: | TBD |
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 125.0 | 445.92 |
The following data is based on the product molecular weight 280.3174 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | TBD |
| In vitro protocol: | TBD |
| In vivo protocol: | TBD |
