WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576486

CAS#: 85275-48-5

Description: ICI-170809 is a 5-HT2 receptor antagonist.

Chemical Structure

CAS# 85275-48-5

Theoretical Analysis

MedKoo Cat#: 576486
Name: ICI-170809
CAS#: 85275-48-5
Chemical Formula: C21H24N2S
Exact Mass: 336.166
Molecular Weight: 336.5
Elemental Analysis: C, 74.96; H, 7.19; N, 8.33; S, 9.53

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: ICI170809; ICI 170809; ICI-170809; ZM 170809; ZM-170809; ZM170809

IUPAC/Chemical Name: 2-Propanamine, N,N,2-trimethyl-1-((3-phenyl-2-quinolinyl)thio)-


InChi Code: InChI=1S/C21H24N2S/c1-21(2,23(3)4)15-24-20-18(16-10-6-5-7-11-16)14-17-12-8-9-13-19(17)22-20/h5-14H,15H2,1-4H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 336.5 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. McAuliffe SJ, Snow HM, Cox B, Smith CC, Noble MI. Interaction between the effects of 5-hydroxytryptamine and adrenaline on the growth of platelet thrombi in the coronary artery of the anaesthetized dog. Br J Pharmacol. 1993 Jun;109(2):405-10. doi: 10.1111/j.1476-5381.1993.tb13583.x. PMID: 8358542; PMCID: PMC2175684.

2. Raco L, Belcher PR, Sim I, McGarrity A, Bernacca GM, Wheatley DJ. Platelet aggregation and high-intensity transient signals (HITS) in a sheep model of mitral valve replacement. J Heart Valve Dis. 1999 Sep;8(5):476-80; discussion 481. PMID: 10517386.

3. Menys VC. Collagen induced human platelet aggregation: serotonin receptor antagonism retards aggregate growth in vitro. Cardiovasc Res. 1993 Nov;27(11):1916-9. doi: 10.1093/cvr/27.11.1916. PMID: 8287397.

4. Menys VC, Smith CC, Lewins P, Farmer RD, Noble MI. Platelet 5-hydroxytryptamine is decreased in a preliminary group of depressed patients receiving the 5-hydroxytryptamine re-uptake inhibiting drug fluoxetine. Clin Sci (Lond). 1996 Jul;91(1):87-92. doi: 10.1042/cs0910087. PMID: 8774265.