WWL-154
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555958

CAS#: 1338574-93-8

Description: WWL-154 is a serine hydrolase inhibitor. Serine hydrolases (SHs) are-​one of the largest and most diverse enzyme classes in mammals. They play fundamental roles in virtually all physiol. processes and are targeted by drugs to treat diseases such as diabetes, obesity, and neurodegenerative disorders.


Chemical Structure

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WWL-154
CAS# 1338574-93-8

Theoretical Analysis

MedKoo Cat#: 555958
Name: WWL-154
CAS#: 1338574-93-8
Chemical Formula: C18H19N3O5
Exact Mass: 357.1325
Molecular Weight: 357.366
Elemental Analysis: C, 60.50; H, 5.36; N, 11.76; O, 22.38

Price and Availability

Size Price Availability Quantity
50.0mg USD 450.0 2 Weeks
100.0mg USD 750.0 2 Weeks
200.0mg USD 1250.0 2 Weeks
500.0mg USD 1950.0 2 Weeks
1.0g USD 2950.0 2 Weeks
2.0g USD 5250.0 2 Weeks
5.0g USD 7950.0 2 Weeks
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Synonym: WWL-154; WWL 154; WWL154;

IUPAC/Chemical Name: 4-(4-Methoxyphenyl)-1-piperazinecarboxylic acid, 4-nitrophenyl ester

InChi Key: TULVXRNEEQWFGU-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H19N3O5/c1-25-16-6-2-14(3-7-16)19-10-12-20(13-11-19)18(22)26-17-8-4-15(5-9-17)21(23)24/h2-9H,10-13H2,1H3

SMILES Code: O=C(N1CCN(C2=CC=C(OC)C=C2)CC1)OC3=CC=C([N+]([O-])=O)C=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 357.366 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Bachovchin DA, Ji T, Li W, Simon GM, Blankman JL, Adibekian A, Hoover H, Niessen S, Cravatt BF. Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20941-6. doi: 10.1073/pnas.1011663107. Epub 2010 Nov 17. PMID: 21084632; PMCID: PMC3000285.

WWL-154

50.0mg / USD 450.0