Hemin dimethyl ester

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 576240

CAS#: 15741-03-4

Description: Hemin dimethyl ester is an iron-containing porphyrinis potentially for the treatment of gastroparesis.

Chemical Structure

Hemin dimethyl ester
CAS# 15741-03-4

Theoretical Analysis

MedKoo Cat#: 576240
Name: Hemin dimethyl ester
CAS#: 15741-03-4
Chemical Formula: C36H36ClFeN4O4
Exact Mass: 679.1775
Molecular Weight: 680.0
Elemental Analysis: C, 63.59; H, 5.34; Cl, 5.21; Fe, 8.21; N, 8.24; O, 9.41

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Dimethylhemin; Hemin dimethyl ester

IUPAC/Chemical Name: iron(III) 13,17-bis(3-methoxy-3-oxopropyl)-2,7,12,18-tetramethyl-3,8-divinylporphyrin-21,22-diide chloride


InChi Code: InChI=1S/C36H36N4O4.ClH.Fe/c1-9-23-19(3)27-15-28-21(5)25(11-13-35(41)43-7)33(39-28)18-34-26(12-14-36(42)44-8)22(6)30(40-34)17-32-24(10-2)20(4)29(38-32)16-31(23)37-27;;/h9-10,15-18H,1-2,11-14H2,3-8H3;1H;/q-2;;+3/p-1/b27-15-,28-15-,29-16-,30-17-,31-16-,32-17-,33-18-,34-18-;;

SMILES Code: [Cl-].[Fe+3].COC(=O)CCC1=C(C)c2cc3nc(cc4[n-]c(cc5nc(cc1[n-]2)c(CCC(=O)OC)c5C)c(C)c4C=C)c(C)c3C=C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 680.0 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Liu Y, Xiong E, Li X, Li J, Zhang X, Chen J. Sensitive electrochemical assay of alkaline phosphatase activity based on TdT-mediated hemin/G-quadruplex DNAzyme nanowires for signal amplification. Biosens Bioelectron. 2017 Jan 15;87:970-975. doi: 10.1016/j.bios.2016.09.069. PubMed PMID: 27668724.

2: Fader CM, Salassa BN, Grosso RA, Vergara AN, Colombo MI. Hemin induces mitophagy in a leukemic erythroblast cell line. Biol Cell. 2016 Apr;108(4):77-95. doi: 10.1111/boc.201500058. PubMed PMID: 26773440.

3: Xue S, Jing P, Xu W. Hemin on graphene nanosheets functionalized with flower-like MnO2 and hollow AuPd for the electrochemical sensing lead ion based on the specific DNAzyme. Biosens Bioelectron. 2016 Dec 15;86:958-65. doi: 10.1016/j.bios.2016.07.111. PubMed PMID: 27498321.

4: Liu F, Tang J, Xu J, Shu Y, Xu Q, Wang H, Hu X. Low potential detection of indole-3-acetic acid based on the peroxidase-like activity of hemin/reduced graphene oxide nanocomposite. Biosens Bioelectron. 2016 Dec 15;86:871-8. doi: 10.1016/j.bios.2016.07.089. PubMed PMID: 27494811.

5: Tripathi AK, Singh N. Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease. J Alzheimers Dis. 2016;51(1):107-21. doi: 10.3233/JAD-151039. PubMed PMID: 26836195.