WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 576238
Description: Hematoporphyrin dicyclohexanyl ether is an iron-free derivative of heme with 4 methyl groups, 2 hydroxyethyl groups, and 2 propionic acid groups attached to the pyrrole rings. Some of these photosensitizing agents are used in the phototherapy of malignant neoplasms.
MedKoo Cat#: 576238
Name: Hematoporphyrin dicyclohexanyl ether
Chemical Formula: C46H58N4O6
Exact Mass: 762.4356
Molecular Weight: 762.99
Elemental Analysis: C, 72.41; H, 7.66; N, 7.34; O, 12.58
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Synonym: Hematoporphyrin dicyclohexanyl ether; HP-Dce
IUPAC/Chemical Name: 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-(cyclohexyloxy)ethyl)-3,8,13,17-tetramethyl-
InChi Key: FEYUPRGTLFQLGY-AZPDBEIKSA-N
InChi Code: InChI=1S/C46H58N4O6/c1-25-33(17-19-43(51)52)39-24-40-34(18-20-44(53)54)26(2)36(48-40)22-41-46(30(6)56-32-15-11-8-12-16-32)28(4)38(50-41)23-42-45(27(3)37(49-42)21-35(25)47-39)29(5)55-31-13-9-7-10-14-31/h21-24,29-32,48-49H,7-20H2,1-6H3,(H,51,52)(H,53,54)/b35-21-,36-22-,37-21-,38-23-,39-24-,40-24-,41-22-,42-23-
SMILES Code: CC(OC1CCCCC1)c2c(C)c3cc4[nH]c(cc5nc(cc6[nH]c(cc2n3)C(=C6CCC(=O)O)C)c(CCC(=O)O)c5C)c(C)c4C(C)OC7CCCCC7
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 762.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Kessel D. Hematoporphyrin and HPD: photophysics, photochemistry and phototherapy. Photochem Photobiol. 1984 Jun;39(6):851-9. doi: 10.1111/j.1751-1097.1984.tb08871.x. PMID: 6235529.
2. Lei TC, Glazner GF, Duffy M, Scherrer L, Pendyala S, Li B, Wang X, Wang H, Huang Z. Optical properties of hematoporphyrin monomethyl ether (HMME), a PDT photosensitizer. Photodiagnosis Photodyn Ther. 2012 Sep;9(3):232-42. doi: 10.1016/j.pdpdt.2012.01.003. Epub 2012 Feb 10. PMID: 22959803.