Gancidin W

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 464254

CAS#: 2873-36-1

Description: Gancidin W is a diketopiperazine isolated from the endophytic actinobacterial genus Streptomyces, SUK10. It is being studied as a potential antimalarial agent.


Chemical Structure

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Gancidin W
CAS# 2873-36-1

Theoretical Analysis

MedKoo Cat#: 464254
Name: Gancidin W
CAS#: 2873-36-1
Chemical Formula: C11H18N2O2
Exact Mass: 210.1368
Molecular Weight: 210.277
Elemental Analysis: C, 62.83; H, 8.63; N, 13.32; O, 15.22

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Gancidin W; Gancidin-W; GW;

IUPAC/Chemical Name: 3-isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione

InChi Key: SZJNCZMRZAUNQT-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H18N2O2/c1-7(2)6-8-11(15)13-5-3-4-9(13)10(14)12-8/h7-9H,3-6H2,1-2H3,(H,12,14)

SMILES Code: CC(CC1NC(C2CCCN2C1=O)=O)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 210.277 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Ahmad SJ, Abdul Rahim MBH, Baharum SN, Baba MS, Zin NM. Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach. J Trop Med. 2017;2017:2189814. doi: 10.1155/2017/2189814. Epub 2017 Oct 16. PMID: 29123551; PMCID: PMC5662797.

2: Zin NM, Baba MS, Zainal-Abidin AH, Latip J, Mazlan NW, Edrada-Ebel R. Gancidin W, a potential low-toxicity antimalarial agent isolated from an endophytic Streptomyces SUK10. Drug Des Devel Ther. 2017 Feb 8;11:351-363. doi: 10.2147/DDDT.S121283. PMID: 28223778; PMCID: PMC5308589.

3: Ghosh S, Kuisiene N, Cheeptham N. The cave microbiome as a source for drug discovery: Reality or pipe dream? Biochem Pharmacol. 2017 Jun 15;134:18-34. doi: 10.1016/j.bcp.2016.11.018. Epub 2016 Nov 17. PMID: 27867014.