FBA 185

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 464251

CAS#: 2866-43-5

Description: FBA 185 is a fluorescent brightener dye.


Chemical Structure

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FBA 185
CAS# 2866-43-5

Theoretical Analysis

MedKoo Cat#: 464251
Name: FBA 185
CAS#: 2866-43-5
Chemical Formula: C18H10N2O2S
Exact Mass: 318.05
Molecular Weight: 318.350
Elemental Analysis: C, 67.91; H, 3.17; N, 8.80; O, 10.05; S, 10.07

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: FBA 185; FBA185; FBA-185; SOF;

IUPAC/Chemical Name: 2,5-bis(benzo[d]oxazol-2-yl)thiophene

InChi Key: UGFSLKRMHPGLFU-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H10N2O2S/c1-3-7-13-11(5-1)19-17(21-13)15-9-10-16(23-15)18-20-12-6-2-4-8-14(12)22-18/h1-10H

SMILES Code: c1(c2sc(c(o3)nc4c3cccc4)cc2)nc(cccc5)c5o1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
To be determined 0.0 0.00

Preparing Stock Solutions

The following data is based on the product molecular weight 318.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Vérité PM , Guido CA , Jacquemin D . First-principles investigation of the double ESIPT process in a thiophene-based dye. Phys Chem Chem Phys. 2019 Jan 30;21(5):2307-2317. doi: 10.1039/c8cp06969g. PMID: 30607419.

2: Lan RF, Yang YF, Ma YZ, Li YQ. The theoretical study of excited-state intramolecular proton transfer of 2,5-bis(benzoxazol-2-yl)thiophene-3,4-diol. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Aug 5;183:37-44. doi: 10.1016/j.saa.2017.04.018. Epub 2017 Apr 18. PMID: 28433832.

3: Zhao J, Zheng Y. Elaboration and controlling excited state double proton transfer mechanism of 2,5-bis(benzoxazol-2-yl)thiophene-3,4-diol. Sci Rep. 2017 Mar 22;7:44897. doi: 10.1038/srep44897. PMID: 28327590; PMCID: PMC5361162.

4: Hao Y , Zheng M , Chen Y . A highly stable and water-soluble fluorescent dye for fluorescence imaging of living cells. J Mater Chem B. 2014 Nov 14;2(42):7369-7374. doi: 10.1039/c4tb01210k. Epub 2014 Sep 26. PMID: 32261961.

5: Nakamura A, Kojima S, Kaniwa M. [The structures of two chemicals sometimes misunderstood as tris-(2,3-dibromopropyl)phosphate in the official analytical method]. Eisei Shikenjo Hokoku. 1986;(104):109-13. Japanese. PMID: 3567421.

6: Anders G. Analysis of river water and drinking water from seven European countries. Environ Qual Saf Suppl. 1975;4:143-56. PMID: 1064531.