LY-3475070
new
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 207152

CAS#: 2375815-63-5

Description: LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alone or in Combination With Pembrolizumab is now under trials for patients with Advanced Cancer.


Chemical Structure

img
LY-3475070
CAS# 2375815-63-5

Theoretical Analysis

MedKoo Cat#: 207152
Name: LY-3475070
CAS#: 2375815-63-5
Chemical Formula: C15H18N4O2
Exact Mass: 286.143
Molecular Weight: 286.335
Elemental Analysis: C, 62.92; H, 6.34; N, 19.57; O, 11.18

Price and Availability

Size Price Availability Quantity
100.0mg USD 2950.0 2 Weeks
200.0mg USD 4250.0 2 Weeks
500.0mg USD 6950.0 2 Weeks
1.0g USD 8950.0 2 Weeks
2.0g USD 14950.0 2 Weeks
Bulk inquiry

Synonym: LY-3475070; LY 3475070; LY3475070;

IUPAC/Chemical Name: 5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione

InChi Key: WHRUIISQCORGKK-KOLCDFICSA-N

InChi Code: InChI=1S/C15H18N4O2/c1-7(2)9-4-11(9)10-5-13(19-18-8(10)3)12-6-16-15(21)17-14(12)20/h5-7,9,11H,4H2,1-3H3,(H2,16,17,20,21)/t9-,11+/m1/s1

SMILES Code: O=C1NC(C(C2=NN=C(C)C([C@@H]3[C@@H](C(C)C)C3)=C2)=CN1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 286.335 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

LY-3475070

100.0mg / USD 2950.0