JUN76288
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 408131

CAS#: 2272976-28-8

Description: JUN76288, also known WEE1-IN-3, is a potent WEE1 kinase inhibitors useful in treatment of cancer and other proliferative diseases. JUN76288 was reported in WO 2019028008. This product has not formal name. For the convenience of scientific communication, we named it by combination its Inchi key (3 letters from the first letter of each section) plus the last 5 digit of its CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).


Chemical Structure

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JUN76288
CAS# 2272976-28-8

Theoretical Analysis

MedKoo Cat#: 408131
Name: JUN76288
CAS#: 2272976-28-8
Chemical Formula: C28H31N7O2
Exact Mass: 497.2539
Molecular Weight: 497.603
Elemental Analysis: C, 67.59; H, 6.28; N, 19.70; O, 6.43

Size Price Shipping out time Quantity
100mg USD 1650 2 Weeks
200mg USD 2950 2 Weeks
500mg USD 3950 2 Weeks
1g USD 4950 2 Weeks
2g USD 7950 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-02. Prices are subject to change without notice.

JUN76288 is in stock.

Synonym: WEE1-IN-3; WEE1-IN 3; WEE1-IN3; JUN76288; JUN-76288; JUN 76288;

IUPAC/Chemical Name: 6-[(2',3'-Dihydro-2'-methylspiro[cyclopropane-1,4'(1'H)-isoquinolin]-7'-yl)amino]-1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one

InChi Key: JSZFIXAMFNNRKS-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37H,1,11-13,16-17H2,2-4H3,(H,29,30,32)

SMILES Code: O=C1N(CC=C)N(C2=NC(C(C)(O)C)=CC=C2)C3=NC(NC4=CC(CN(C)C5)=C(C65CC6)C=C4)=NC=C31

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 497.603 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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WO 2019028008