WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 408131
CAS#: 2272976-28-8
Description: JUN76288, also known WEE1-IN-3, is a potent WEE1 kinase inhibitors useful in treatment of cancer and other proliferative diseases. JUN76288 was reported in WO 2019028008. This product has not formal name. For the convenience of scientific communication, we named it by combination its Inchi key (3 letters from the first letter of each section) plus the last 5 digit of its CAS#) according to Hodoodo Chemical Nomenclature (https://hodoodo.com/hodoodo-chemical-nomenclature).
MedKoo Cat#: 408131
Name: JUN76288
CAS#: 2272976-28-8
Chemical Formula: C28H31N7O2
Exact Mass: 497.2539
Molecular Weight: 497.603
Elemental Analysis: C, 67.59; H, 6.28; N, 19.70; O, 6.43
JUN76288 is in stock.
Synonym: WEE1-IN-3; WEE1-IN 3; WEE1-IN3; JUN76288; JUN-76288; JUN 76288;
IUPAC/Chemical Name: 6-[(2',3'-Dihydro-2'-methylspiro[cyclopropane-1,4'(1'H)-isoquinolin]-7'-yl)amino]-1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one
InChi Key: JSZFIXAMFNNRKS-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37H,1,11-13,16-17H2,2-4H3,(H,29,30,32)
SMILES Code: O=C1N(CC=C)N(C2=NC(C(C)(O)C)=CC=C2)C3=NC(NC4=CC(CN(C)C5)=C(C65CC6)C=C4)=NC=C31
The following data is based on the product molecular weight 497.603 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
WO 2019028008
