WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 408131

CAS#: 2272976-28-8

Description: JUN76288, also known WEE1-IN-3, is a potent WEE1 kinase inhibitors useful in treatment of cancer and other proliferative diseases. This product has not formal name. For the convenience of scientific communication, we named it by combining its Inchi key (3 letters from the first letter of each section) with the last 5 digits of its CAS number or its molecule weight if its CAS number is not available (see MedKoo Chemical Nomenclature, https://www.medkoo.com/page/naming).

Chemical Structure

CAS# 2272976-28-8

Theoretical Analysis

MedKoo Cat#: 408131
Name: JUN76288
CAS#: 2272976-28-8
Chemical Formula: C28H31N7O2
Exact Mass: 497.2539
Molecular Weight: 497.603
Elemental Analysis: C, 67.59; H, 6.28; N, 19.70; O, 6.43

Price and Availability

Size Price Availability Quantity
100.0mg USD 1650.0 2 Weeks
200.0mg USD 2950.0 2 Weeks
500.0mg USD 3950.0 2 Weeks
1.0g USD 4950.0 2 Weeks
2.0g USD 7950.0 2 Weeks
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Synonym: WEE1-IN-3; WEE1-IN 3; WEE1-IN3; JUN76288; JUN-76288; JUN 76288;

IUPAC/Chemical Name: 6-[(2',3'-Dihydro-2'-methylspiro[cyclopropane-1,4'(1'H)-isoquinolin]-7'-yl)amino]-1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one


InChi Code: InChI=1S/C28H31N7O2/c1-5-13-34-25(36)20-15-29-26(32-24(20)35(34)23-8-6-7-22(31-23)27(2,3)37)30-19-9-10-21-18(14-19)16-33(4)17-28(21)11-12-28/h5-10,14-15,37H,1,11-13,16-17H2,2-4H3,(H,29,30,32)

SMILES Code: O=C1N(CC=C)N(C2=NC(C(C)(O)C)=CC=C2)C3=NC(NC4=CC(CN(C)C5)=C(C65CC6)C=C4)=NC=C31

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 497.603 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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WO 2019028008


100.0mg / USD 1650.0