Gevotroline

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 575861

CAS#: 107266-06-8

Description: Gevotroline is a sigma receptor ligand that has been shown to elevate corticosterone levels in plasma.

Chemical Structure

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Gevotroline
CAS# 107266-06-8
Instruction

Theoretical Analysis

MedKoo Cat#: 575861
Name: Gevotroline
CAS#: 107266-06-8
Chemical Formula: C19H20FN3
Exact Mass: 309.16
Molecular Weight: 309.390
Elemental Analysis: C, 73.76; H, 6.52; F, 6.14; N, 13.58

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: Gevotroline

IUPAC/Chemical Name: 1H-Pyrido(4,3-b)indole, 8-fluoro-2,3,4,5-tetrahydro-2-(3-(3-pyridinyl)propyl)-

InChi Key: RZXHTPCHKSYGIB-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H20FN3/c20-15-5-6-18-16(11-15)17-13-23(10-7-19(17)22-18)9-2-4-14-3-1-8-21-12-14/h1,3,5-6,8,11-12,22H,2,4,7,9-10,13H2

SMILES Code: Fc1ccc2[nH]c3CCN(CCCc4cccnc4)Cc3c2c1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:
Product Data
Instruction:
View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 309.390000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Djeni TN, Kouame KH, Ake FDM, Amoikon LST, Dje MK, Jeyaram K. Microbial Diversity and Metabolite Profiles of Palm Wine Produced From Three Different Palm Tree Species in Côte d'Ivoire. Sci Rep. 2020 Feb 3;10(1):1715. doi: 10.1038/s41598-020-58587-2. PMID: 32015447; PMCID: PMC6997158. 2. Matheson GK, Guthrie D, Bauer C, Knowles A, White G, Ruston C. Sigma receptor ligands alter concentrations of corticosterone in plasma in the rat. Neuropharmacology. 1991 Jan;30(1):79-87. doi: 10.1016/0028-3908(91)90046-e. PMID: 1675451.